Key result
Short-term cold exposure significantly increased the T-peak to T-end interval and T-wave amplitude while shortening the QTc interval, with similar changes observed in both hypertensive men and controls.
Why the study?
Does short-term cold exposure alter cardiac electrical function and autonomic regulation in untreated hypertensive men compared to normotensive controls?
Observational (n=83)
No
Does short-term cold exposure alter cardiac electrical function and autonomic regulation in untreated hypertensive men compared to normotensive controls?
Mean Difference: 5 (95% CI 3–7)
Absolute Event Rate: 72% vs 67%
p-value: p=<0.001
Short-term cold exposure alters repolarization similarly regardless of hypertension status; extends autonomic response data to untreated hypertensive men.
The aim of our study was to assess the effect of short-term cold exposure, typical in subarctic climate, on cardiac electrical function among untreated middle-aged hypertensive men.
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Hintsala et al. (2014) conducted an observational in Untreated hypertension (n=83). Short-term cold exposure vs. Baseline (warm environment) was evaluated on T-peak to T-end interval in lead II (hypertensive men) (MD 5 ms, 95% CI 3-7, p=<0.001). Short-term cold exposure significantly increased the T-peak to T-end interval and T-wave amplitude while shortening the QTc interval, with similar changes observed in both hypertensive men and controls.
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