Key result
An outbreak of enterovirus D68 B3 lineage in Stockholm, Sweden, resulted in 74 positive cases out of 495 respiratory samples, with 10 patients experiencing severe symptoms and one death.
Observational (n=495)
No
The report highlights an outbreak of the EV-D68 B3 lineage in Sweden in 2016, associated with severe respiratory and neurological symptoms primarily in young children.
Alerts clinicians to EV-D68 B3 outbreaks with severe pediatric illness; leaves open needs for enhanced surveillance and lineage-specific studies.
We report an enterovirus D68 (EV-D68) outbreak in Stockholm Sweden in 2016. Between 22 August and 25 September EV-D68 was detected in 74/495 respiratory samples analysed at the Karolinska University Hospital. During the peak week, 30/91 (33%) samples were EV-D68 positive. Viral protein (VP)P4/VP2 sequencing revealed that cases were caused by B3 lineage strains. Forty-four (59%) EV-D68-positive patients were children aged ≤ 5 years. Ten patients had severe respiratory or neurological symptoms and one died.
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Dyrdak et al. (2016) conducted an observational in Enterovirus D68 (EV-D68) infection (n=495). Enterovirus D68 (EV-D68) B3 lineage was evaluated on Detection of EV-D68. An outbreak of enterovirus D68 B3 lineage in Stockholm, Sweden, resulted in 74 positive cases out of 495 respiratory samples, with 10 patients experiencing severe symptoms and one death.
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