Key result
Among patients with vasospastic angina, surviving an out-of-hospital cardiac arrest was associated with a significantly higher risk of major adverse cardiac events (HR 3.25; 95% CI 1.39-7.61; P<0.01).
Why the study?
Does a history of out-of-hospital cardiac arrest increase the risk of major adverse cardiac events in patients with vasospastic angina?
Cohort (n=1,429)
Yes
Does a history of out-of-hospital cardiac arrest increase the risk of major adverse cardiac events in patients with vasospastic angina?
Hazard Ratio: 3.25 (95% CI 1.39–7.61)
Absolute Event Rate: 72% vs 92%
p-value: p=<0.01
Vasospastic angina patients who survive an out-of-hospital cardiac arrest represent a high-risk population with a significantly increased rate of subsequent major adverse cardiac events.
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Survivors warrant closer surveillance; extends risk stratification in vasospastic angina but leaves open need for prospective validation.
Takagi et al. (2011) conducted a cohort in Vasospastic angina (n=1,429). Out-of-hospital cardiac arrest (OHCA) vs. No out-of-hospital cardiac arrest was evaluated on Survival free from major adverse cardiac events (HR 3.25, 95% CI 1.39-7.61, p=<0.01). Among patients with vasospastic angina, surviving an out-of-hospital cardiac arrest was associated with a significantly higher risk of major adverse cardiac events (HR 3.25; 95% CI 1.39-7.61; P<0.01).
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