Key result
Higher pre-gravid blood pressure was associated with a greater blood pressure drop in early pregnancy, whereas women with the lowest pre-gravid blood pressure showed no obvious drop throughout pregnancy.
Population
1,282 normotensive women with a singleton pregnancy, complete baseline information, and three or more…
Design
Cohort
Follow-up
throughout pregnancy up to delivery
Authors
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Pre-gravid BP may stratify pregnancy trajectories; challenges universal mid-trimester drop but hypothesis-generating pending prospective confirmation.
Cohort (n=1,282)
No
This study challenges the widely accepted concept of a mid-trimester blood pressure drop during pregnancy, demonstrating that blood pressure trajectories depend heavily on pre-gravid blood pressure levels.
Shen et al. (2017) conducted a cohort in Pregnancy (n=1,282). Pre-gravid blood pressure vs. Lowest pre-gravid blood pressure tertile was evaluated on Trajectory of blood pressure change during pregnancy. Higher pre-gravid blood pressure was associated with a greater blood pressure drop in early pregnancy, whereas women with the lowest pre-gravid blood pressure showed no obvious drop throughout pregnancy.
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