Key result
Thiazide diuretics effectively reduce blood pressure as monotherapy, enhance other antihypertensive agents, and lower hypertension-related morbidity and mortality.
Why the study?
Do thiazide diuretics reduce blood pressure and hypertension-related morbidity and mortality in patients with hypertension?
Population
Patients with hypertension
Design
Review
Authors
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Supports thiazide use as foundational therapy; leaves open optimal combinations with newer agents in contemporary populations.
Do thiazide diuretics reduce blood pressure and hypertension-related morbidity and mortality in patients with hypertension?
Thiazide diuretics are effective for long-term therapy in hypertension, reducing blood pressure and associated morbidity and mortality.
Ernst et al. (2009) studied this question. Thiazide diuretics effectively reduce blood pressure as monotherapy, enhance other antihypertensive agents, and lower hypertension-related morbidity and mortality.
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