Why the study?
Are diuretics safe and effective as first-line therapy for essential hypertension?
Population
Patients with essential hypertension
Design
Review
Authors
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Maintains diuretics as first-line for hypertension; leaves open need for updated randomized safety data.
Are diuretics safe and effective as first-line therapy for essential hypertension?
Despite concerns regarding long-term metabolic and hemodynamic side effects, diuretics remain recommended as first-line therapy for essential hypertension.
Richard I. Ogilvie (1983) studied this question.
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