Why the study?
Does hydrochlorothiazide reduce peripheral venous reactivity in subjects with essential hypertension?
Population
14 subjects with essential hypertension (and 9 normotensive volunteers for comparison)
Comparison
Hydrochlorothiazide 150 mg per day and 450 mg… vs Placebo therapy
Design
Other, single-blind
Authors
Loading...
May support venodilation as HCT mechanism in hypertension; leaves open confirmation in randomized trials.
Does hydrochlorothiazide reduce peripheral venous reactivity in subjects with essential hypertension?
Hydrochlorothiazide therapy reduces the response of the venous capacitance bed to neurogenic stimuli in hypertensive patients.
Ogilvie et al. (1970) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: