Key result
Baseline left atrial diameter of 5.5 cm or greater, volume of 200 ml or greater, and fragmentation duration over 190 ms predicted poor efficacy of radiofrequency ablation in patients with atrial fibrillation.
Why the study?
Do baseline electromechanical parameters of the left atrium predict the success of radiofrequency ablation in patients with atrial fibrillation?
Cohort (n=94)
No
Do baseline electromechanical parameters of the left atrium predict the success of radiofrequency ablation in patients with atrial fibrillation?
p-value: p=0.0001
Baseline left atrial diameter >4.5 cm and volume >105-110 ml, along with extensive fragmented activity, are critical predictors of radiofrequency ablation failure in patients with atrial fibrillation.
May identify AF patients unlikely to benefit from ablation; hypothesis-generating and requires prospective validation.
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Bockeriа et al. (2014) conducted a cohort in Atrial fibrillation (n=94). Baseline electromechanical remodeling parameters vs. Patients with less severe baseline remodeling was evaluated on Maintenance of sinus rhythm vs recurrence of atrial fibrillation (p=0.0001). Baseline left atrial diameter of 5.5 cm or greater, volume of 200 ml or greater, and fragmentation duration over 190 ms predicted poor efficacy of radiofrequency ablation in patients with atrial fibrillation.
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