Key result
Patients with a left atrial volume index ≥29 ml/m2 and PA-TDI duration ≥143 ms had a 10.88-fold increased risk of atrial tachyarrhythmia recurrence after catheter ablation compared to those with lower values.
Why the study?
Does increased atrial remodeling (LAVI ≥29 ml/m2 and/or PA-TDI ≥143 ms) increase atrial tachyarrhythmia recurrence in patients with paroxysmal atrial fibrillation undergoing radiofrequency catheter ablation?
Cohort (n=100)
No
Does increased atrial remodeling (LAVI ≥29 ml/m2 and/or PA-TDI ≥143 ms) increase atrial tachyarrhythmia recurrence in patients with paroxysmal atrial fibrillation undergoing radiofrequency catheter ablation?
Hazard Ratio: 10.88 (95% CI 2.96–54.52)
Absolute Event Rate: 66% vs 12%
p-value: p=0.0001
Preprocedural echocardiographic assessment combining LAVI and PA-TDI duration strongly predicts atrial tachyarrhythmia recurrence after a single radiofrequency catheter ablation for paroxysmal atrial fibrillation.
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May refine pre-ablation recurrence risk stratification; leaves open whether parameters should alter patient selection or adjunctive therapy.
Ejima et al. (2014) conducted a cohort in Paroxysmal atrial fibrillation (PAF) (n=100). High left atrial volume index (≥29 ml/m2) and prolonged PA-TDI duration (≥143 ms) vs. Low left atrial volume index (<29 ml/m2) and short PA-TDI duration (<143 ms) was evaluated on Atrial tachyarrhythmia (AF/AT) recurrence after radiofrequency catheter ablation (HR 10.88, 95% CI 2.96-54.52, p=0.0001). Patients with a left atrial volume index ≥29 ml/m2 and PA-TDI duration ≥143 ms had a 10.88-fold increased risk of atrial tachyarrhythmia recurrence after catheter ablation compared to those with lower values.
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