Key result
The Cox Maze IV procedure maintained sinus rhythm in 66% of patients with mitral valve disease, atrial fibrillation, and high pulmonary hypertension at 2 years.
Why the study?
The study aimed to analyze surgical outcomes in patients with mitral valve disease, concomitant atrial fibrillation, and severe pulmonary hypertension, and identify predictors of recurrent atrial fibrillation.
Does the Cox Maze IV procedure improve the maintenance of sinus rhythm in patients with mitral valve disease, atrial fibrillation, and high pulmonary hypertension?
Cohort (n=151)
Does the Cox Maze IV procedure improve the maintenance of sinus rhythm in patients with mitral valve disease, atrial fibrillation, and high pulmonary hypertension?
The Cox Maze IV procedure is effective for maintaining sinus rhythm in patients with mitral valve disease and pulmonary hypertension, though severe pulmonary hypertension (>60 mmHg) and long AF duration (>3 years) strongly predict recurrence.
May support rhythm control consideration in selected mitral cases; leaves open need for randomized confirmation in this population.
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Трофимов et al. (2020) conducted a cohort in Mitral valve disease with concomitant atrial fibrillation and high pulmonary hypertension (n=151). Cox Maze IV procedure with mitral valve surgery vs. Mitral valve surgery alone was evaluated on Maintenance of sinus rhythm. The Cox Maze IV procedure maintained sinus rhythm in 66% of patients with mitral valve disease, atrial fibrillation, and high pulmonary hypertension at 2 years.
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