Key result
Combining septal myectomy with transaortic mitral valve repair in HOCM patients with severe mitral regurgitation led to a greater reduction in regurgitation degree than isolated myectomy (P<0.05).
Why the study?
The study was conducted to evaluate the efficacy of isolated transaortic septal myectomy versus septal myectomy combined with mitral valve repair in patients with hypertrophic obstructive cardiomyopathy.
Does combining septal myectomy with transaortic mitral valve repair improve mitral regurgitation compared to isolated septal myectomy in patients with hypertrophic obstructive cardiomyopathy?
Population
62 patients with obstructive hypertrophic cardiomyopathy
Comparison
Septal myectomy plus edge-to-edge mitral valve repair vs isolated Morrow septal myectomy
Design
Cohort study
Follow-up
Up to 60 months
Authors
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May support combined myectomy and mitral repair in selected HOCM; leaves open need for randomized confirmation.
Cohort (n=62)
Does combining septal myectomy with transaortic mitral valve repair improve mitral regurgitation compared to isolated septal myectomy in patients with hypertrophic obstructive cardiomyopathy?
Absolute Event Rate: 1.4% vs 1.7%
p-value: p=<0.05
In patients with hypertrophic obstructive cardiomyopathy and severe mitral regurgitation, combining septal myectomy with transaortic mitral valve repair provides a more significant long-term reduction in mitral regurgitation compared to isolated myectomy.
Velieva et al. (2020) conducted a cohort in Obstructive hypertrophic cardiomyopathy (n=62). Septal myectomy combined with transaortic mitral valve repair vs. Isolated septal myectomy was evaluated on Degree of mitral regurgitation (p=<0.05). Combining septal myectomy with transaortic mitral valve repair in HOCM patients with severe mitral regurgitation led to a greater reduction in regurgitation degree than isolated myectomy (P<0.05).
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