Key result
Pre-existing alterations in sinoatrial node exit sites and atrial conduction disorders were identified in 3 pediatric patients who developed early post-operative sinus node dysfunction.
Why the study?
Early post-operative sinus node dysfunction is common after surgical correction of congenital heart defects in paediatric patients, but its pathophysiology remains incompletely understood.
Case Report (n=3)
Pre-existing alterations in sinoatrial node exit sites and atrial conduction disorders may predispose pediatric patients with congenital heart defects to early post-operative sinus node dysfunction.
Should not change surgical planning in congenital heart disease; leaves open whether mapping identifies at-risk patients.
Early post-operative sinus node dysfunction (SND) is common in paediatric patients undergoing surgical correction of congenital heart defects (CHD). At present, the pathophysiology of these arrhythmias is incompletely understood. In this case series, we present three paediatric patients in whom we performed intraoperative epicardial mapping and who developed early post-operative SND. All patients had either an inferior or multiple sinoatrial node (SAN) exit sites, in addition to extensive conduction disorders at superior and inferior right atrium. Our findings contribute to the hypothesis that pre-existing alterations in SAN exit sites in combination with atrial conduction disorders may predispose paediatric patients with CHD for early post-operative SND. Such insights in the development of arrhythmias are crucial as it may be the first step in identifying high-risk patients.
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Misier et al. (2022) conducted a case report in Congenital heart defects (CHD) (n=3). Pre-existing alterations in sinoatrial node exit sites and atrial conduction disorders was evaluated on Early post-operative sinus node dysfunction (SND). Pre-existing alterations in sinoatrial node exit sites and atrial conduction disorders were identified in 3 pediatric patients who developed early post-operative sinus node dysfunction.
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