Population
Frog sartorii muscles contracting isotonically at 20 degrees
Comparison
Repetitive stimuli, epinephrine pretreatment… vs Resting state or untreated state
Design
Preclinical
Authors
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These frog muscle findings warrant no clinical change; leaves open translation to mammalian cardiac metabolism.
This basic science study demonstrates that the conversion of phosphorylase b to a in frog muscle is influenced by stimulation rate, epinephrine, and transmembrane potential, but not by external work.
Danforth et al. (1964) studied this question.
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