Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
May 1, 1988Acta Physiologica Scandinavica

Skeletal muscle glucolysis, glycogenolysis and glycogen phosphorylase during electrical stimulation in man

View Full Paper
Ask AI
Bookmark
Share

Key result

Electrical stimulation with occluded blood circulation increased glycogenolytic and glucolytic rates by about 30% during a second contraction compared with the first (P<0.05).

Why the study?

How does blood circulation occlusion affect glycogenolytic and glucolytic rates during electrical stimulation in human skeletal muscle?

Population

Human subjects (quadriceps muscle)

Comparison

Electrical stimulation at 20 Hz with occluded… vs Same electrical stimulation protocol with intact…

Design

Other

Authors

JRJun RenGeneral CardiologyDCD. ChasiotisKarolinska University HospitalMBMats BergströmUppsala University

Discussion

Loading...

Member takes

Implication

May enhance glycolytic flux in ischemic muscle; hypothesis-generating for metabolic regulation in vascular disease.

Structured PICO

How does blood circulation occlusion affect glycogenolytic and glucolytic rates during electrical stimulation in human skeletal muscle?

P
Population
Human subjects (quadriceps muscle)
I
Intervention
Electrical stimulation at 20 Hz (two 10 s periods separated by a 60 s pause) with occluded blood circulation
C
Comparator
Same electrical stimulation protocol with intact blood circulation
O
Outcome
Phosphorylase activity, glycogenolytic and glucolytic ratessurrogate

Main Result

p-value: p=<0.05

Increased glycogenolytic and glucolytic rates during repeated muscle contractions with occluded circulation are driven by high inorganic phosphate and low phosphocreatine levels.

Cite This Study

Ren et al. (1988) studied this question. Electrical stimulation with occluded blood circulation vs. Electrical stimulation with intact blood circulation was evaluated on Glycogenolytic and glucolytic rates (p=<0.05). Electrical stimulation with occluded blood circulation increased glycogenolytic and glucolytic rates by about 30% during a second contraction compared with the first (P<0.05).

synapsesocial.com/papers/6a9313ef9bdf9f6debc6b77chttps://doi.org/10.1111/j.1748-1716.1988.tb08386.x
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Phosphorylase activity in needle biopsy samples‐factors influencing transformation1988 · 22 citations
  2. 2Improved efficiency of n-CdSe thin-film photoelectrodes by zinc surface treatment1982 · 85 citations
  3. 3Reversal of phosphorylase activation in muscle despite continued contractile activity1979 · 53 citations