Key result
In diabetic patients with peripheral arterial disease, brachial-ankle pulse wave velocity was significantly lower in the affected legs (median 1221 cm/sec) than in non-affected legs (median 1607 cm/sec).
Why the study?
Does brachial-ankle pulse wave velocity (baPWV) differ in lower-limb arteries among diabetic patients with peripheral arterial disease compared to healthy controls and non-affected legs?
Population
203 subjects, comprising 101 healthy control subjects and 102 type 2 diabetic patients.
Comparison
Measurement of brachial-ankle pulse wave… vs Healthy control subjects, and intra-patient…
Design
Cross-sectional
Authors
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Lower baPWV in affected legs may aid PAD detection in diabetes; leaves open its value as a diagnostic marker pending prospective studies.
Cross-Sectional (n=203)
No
Does brachial-ankle pulse wave velocity (baPWV) differ in lower-limb arteries among diabetic patients with peripheral arterial disease compared to healthy controls and non-affected legs?
Absolute Event Rate: 1221% vs 1607%
p-value: p=0.021
Widening of the right-left difference in brachial-ankle pulse wave velocity may serve as a novel marker for peripheral arterial disease in diabetic patients.
Yokoyama et al. (2003) conducted a cross-sectional in Type 2 Diabetes Mellitus with and without Peripheral Arterial Disease (n=203). Peripheral Arterial Disease (PAD) vs. Non-affected legs / Diabetic patients without PAD was evaluated on Brachial-ankle pulse wave velocity (baPWV) in affected vs non-affected legs of diabetic patients with PAD (p=0.021). In diabetic patients with peripheral arterial disease, brachial-ankle pulse wave velocity was significantly lower in the affected legs (median 1221 cm/sec) than in non-affected legs (median 1607 cm/sec).
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