Why the study?
Does pressure-dependent reduction in distal coronary artery diameter lead to an overestimation of coronary flow velocity reserve (CFVR)?
Does pressure-dependent reduction in distal coronary artery diameter lead to an overestimation of coronary flow velocity reserve (CFVR)?
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Theoretical modeling indicates that pressure-dependent reductions in distal coronary diameter may artificially enhance CFVR, potentially causing erroneous clinical assessments of stenosis severity.
Siebes et al. (2002) studied this question.
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