Key result
Retrograde coronary venous ethanol ablation eliminates intractable VT shocks through 6 months of follow-up.
Why the study?
Ventricular tachycardia originating in the LV summit in patients with structural heart disease can be challenging, and failed RF ablation may necessitate unconventional treatments such as ethanol ablation.
Does retrograde coronary venous ethanol ablation prevent recurrent ventricular tachycardia in a patient with refractory VT after failed RF ablation and SBRT?
Case Report (n=1)
Does retrograde coronary venous ethanol ablation prevent recurrent ventricular tachycardia in a patient with refractory VT after failed RF ablation and SBRT?
Retrograde coronary venous ethanol ablation can serve as a viable and safe bail-out strategy for highly refractory ventricular tachycardia originating from the LV summit when conventional therapies like RF ablation and SBRT fail.
Answers are grounded in this paper and cite their sources.
May offer bail-out for refractory LV summit VT after failed RF/SBRT; leaves open need for prospective validation.
Radiofrequency (RF) ablation is a well-established and frequently used treatment modality for drug-refractory ventricular tachycardias (VT).1 The left ventricular (LV) summit represents a common site of origin of focal idiopathic VT. Less frequently, it can host the complex arrhythmogenic substrate in patients with structural heart disease such as dilated cardiomyopathy or aortic valve disease. Such scenario may require repeated ablation procedures with an uncertain outcome. In the case of failed RF ablation, several unconventional treatment modalities, including bipolar RF ablation, stereotactic body radiation therapy (SBRT), and ethanol ablation, have been proposed.
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Stojadinovic et al. (2022) conducted a case report in Drug-refractory ventricular tachycardia (n=1). Retrograde coronary venous ethanol ablation was evaluated on Freedom from implantable cardioverter-defibrillator shocks. Retrograde coronary venous ethanol ablation successfully suppressed intractable ventricular tachycardia, with the patient remaining free of ICD shocks during 6 months of follow-up.
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