Key result
Critical isthmus-targeted ablation with high-density mapping is linked to ~60% lower atypical atrial flutter recurrence.
Why the study?
Data on clinical outcomes and factors associated with arrhythmia recurrence following high-density mapping for atypical atrial flutter ablation were scarce.
Does catheter ablation using high-density mapping improve freedom from atrial flutter recurrence in patients with atypical atrial flutter?
Population
61 patients with 94 atypical atrial flutters undergoing catheter ablation
Comparison
Catheter ablation using a high-density mapping system and a grid-shaped mapping catheter
Design
Single-center, prospective, observational cohort study
Follow-up
1.3 [1.0-2.1] years
Authors
Loading...
May inform isthmus targeting in atypical flutter ablation; hypothesis-generating for high-density mapping pending randomized trials.
Cohort (n=61)
No
Does catheter ablation using high-density mapping improve freedom from atrial flutter recurrence in patients with atypical atrial flutter?
Hazard Ratio: 0.4 (95% CI 0.16–0.97)
p-value: p=0.04
High-density mapping successfully identifies the majority of atypical atrial flutter circuits, and critical isthmus ablation is associated with improved long-term freedom from recurrence.
Abeln et al. (2023) conducted a cohort in Atypical atrial flutters (n=61). Critical isthmus-targeted ablation was evaluated on Atrial flutter recurrence (HR 0.4, 95% CI 0.16-0.97, p=0.04). Critical isthmus-targeted ablation during high-density mapping for atypical atrial flutter was associated with a reduced risk of recurrence (HR 0.4; 95% CI 0.16-0.97; p=0.04).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: