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June 4, 2026Clinics0 citationsOpen Access

Inflammatory Score Predicts Hematoma Expansion and Functional Outcomes After ICH

A novel inflammatory score predicts hematoma expansion and 90‑day functional outcomes after spontaneous intracerebral hemorrhage

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Authors

XLXianxian LiTongji HospitalYJYuchao JiaTianjin HospitalJYJiahe YeTongji Hospital

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Overview

Retrospective analysis identifies an inflammatory score that predicts outcomes in intracerebral hemorrhage, suggesting it may improve risk assessment.

Key Points

  • To assess the prognostic value of an inflammatory score in predicting hematoma expansion and 90-day outcomes in patients with spontaneous intracerebral hemorrhage.
  • Retrospective analysis of acute ICH admissions at Tongji Hospital from 2012 to 2024.
  • Inflammatory score derived from blood biomarkers within 24 hours of admission.
  • Analyzed hematoma expansion and outcomes using multivariable models and imputation techniques.
  • Hematoma expansion occurred in 298 of 1047 patients (28.5%).
  • The inflammatory score was associated with hematoma expansion (adjusted OR 1.18) and poor function (adjusted OR 1.27).
  • Adding the score improved AUC for hematoma expansion (0.681 to 0.709, p=0.007) and mortality (0.815 to 0.838, p=0.036).

Cite This Study

Li et al. (2026) studied this question.

synapsesocial.com/papers/6a211549d499ed480b16e885https://doi.org/10.1016/j.clinsp.2026.101004
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1ABSTRACT NUMBER: ESOC2026A57 INCREMENTAL VALUE OF INFLAMMATORY BIOMARKERS AS COMPLEMENT TO ICH SCORE IN PREDICTING INTRACEREBRAL HEMORRHAGE PROGNOSIS2026
  2. 2Predicting hematoma growth in spontaneous intracerebral hemorrhage: A simplified non-contrast computed tomography based five-point grading approach.2025
  3. 3Development of a Novel Prognostic Inflammation Index to Predict Poor Outcomes in Patients With Intracerebral Hemorrhage: A Longitudinal Study2026
  4. 4Monocyte-to-high-density lipoprotein cholesterol ratio predicts hematoma expansion and poor outcomes in patients with spontaneous intracerebral hemorrhage2026
  5. 5Abstract WP216: MRI Biomarkers Improve Prognostic Accuracy Beyond the ICH Score in Acute Intracerebral Hemorrhage2026