Key result
The LDL receptor plays an important role in various viral and parasitic infections, serving as a port of entry or being essential for the infection cycle, and is a potential target for treatment.
Why the study?
Although the role of the LDL receptor concerning lipids is well known, its role in viral and parasitic infections and in regulating inflammatory responses is poorly understood.
Beyond lipid metabolism, the LDL receptor plays a crucial role in various viral and parasitic infections, making it a potential therapeutic target.
LDL receptor modulation merits exploration as antiviral strategy; hypothesis-generating and should not yet change practice.
Although the role of the LDL receptor concerning lipids is well known, its role in various viral and parasitic infections, and in regulating the inflammatory response is poorly understood. Several infectious agents use the LDL receptor as a port of entry, and others depend on it for their cycle of infection. In this review, we focus on the discovery, structure, and normal function of the LDL receptor, as well as its role in a selection of infections. The LDL receptor plays an important role in certain infections and is a potential target for treatment deserving further research.
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Aldana-Bitar et al. (2021) conducted a review in Viral and parasitic infections. LDL receptor was evaluated. The LDL receptor plays an important role in various viral and parasitic infections, serving as a port of entry or being essential for the infection cycle, and is a potential target for treatment.
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