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This review aims to summarize the progress in the development of 1,2,3-triazole derivatives as antidiabetic agents over the last decade.

Recent advancements in 1,2,3-triazole-based derivatives as antidiabetic agents: Synthesis and biological insights

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Review analyzes advancements in 1,2,3-triazole derivatives for type-2 diabetes treatment, suggesting potential therapeutic impacts.

This review aims to summarize the progress in the development of 1,2,3-triazole derivatives as antidiabetic agents over the last decade.
Comprehensive review of existing literature on 1,2,3-triazole derivatives
Analysis of synthesis methods, particularly copper-catalyzed azide–alkyne cycloaddition
Evaluation of biological properties and potential as therapeutic agents
Highlighted the metabolic stability and favorable properties of 1,2,3-triazole scaffolds
Identified significant advancements in synthesizing structurally diverse libraries for biological testing
Demonstrated potential efficacy of new derivatives in influencing enzymatic activity related to diabetes

Moura et al. (2026) studied this question.

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