June 2, 2016EP EuropaceOpen Access

Limited left atrial surgical ablation effectively treats atrial fibrillation but decreases left atrial function

Q: What is the clinical evidence from this study?

Study design: Cohort. Population: Atrial fibrillation (n=72). Intervention: Limited left atrial surgical ablation vs. Epicardial pulmonary vein isolation (PVI) only. Primary outcome: Sinus rhythm maintenance at 1-year follow-up (p=0.18).

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Key result

Limited left atrial surgical ablation resulted in similar sinus rhythm maintenance at 1 year compared to PVI alone (67% vs 81%, P=0.18), but significantly decreased left atrial transport function.

Why the study?

Does limited left atrial surgical ablation compared to PVI alone maintain left atrial function in patients undergoing concomitant cardiac surgery?

Population

72 patients scheduled for valve surgery and/or coronary revascularization with atrial fibrillation…

Comparison

Limited left atrial surgical ablation… vs Epicardial pulmonary vein isolation only…

Design

Cohort

Follow-up

12 months

Authors

MCMarieke G. Compier LTL. F. Tops JBJerry Braun

Discussion

Member takes

Overview

May warrant caution with limited LA ablation in concomitant surgery; leaves open optimal strategies balancing rhythm and function.

Study Design

Type

Cohort (n=72)

Structured PICO

Does limited left atrial surgical ablation compared to PVI alone maintain left atrial function in patients undergoing concomitant cardiac surgery?

Population

72 patients with atrial fibrillation undergoing cardiac surgery, comparing limited left atrial surgical ablation to pulmonary vein isolation alone with 12-month follow-up.

Exposure

Limited left atrial surgical ablation (epicardial pulmonary vein isolation and additional endo-epicardial lines using bipolar radiofrequency) concomitant to cardiac surgery

Comparator

Epicardial pulmonary vein isolation (PVI) only concomitant to cardiac surgery

Outcome

Left atrial dimensions and function assessed on two-dimensional echocardiography at 3- and 12-month follow-upsurrogate

Main Result

Absolute Event Rate: 67% vs 81%

p-value: p=0.18

Limited left atrial surgical ablation during cardiac surgery decreases left atrial function and compliance compared to PVI alone, despite similar rates of sinus rhythm maintenance.

Cite This Study

Compier et al. (2016) conducted a cohort in Atrial fibrillation (n=72). Limited left atrial surgical ablation vs. Epicardial pulmonary vein isolation (PVI) only was evaluated on Sinus rhythm maintenance at 1-year follow-up (p=0.18). Limited left atrial surgical ablation resulted in similar sinus rhythm maintenance at 1 year compared to PVI alone (67% vs 81%, P=0.18), but significantly decreased left atrial transport function.

synapsesocial.com/papers/6a21189b6bd086c0991e4a60 https://doi.org/10.1093/europace/euw106

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June 2, 2016EP EuropaceOpen Access

Limited left atrial surgical ablation effectively treats atrial fibrillation but decreases left atrial function

View Full Paper

Ask AI

Bookmark

Key result

Limited left atrial surgical ablation resulted in similar sinus rhythm maintenance at 1 year compared to PVI alone (67% vs 81%, P=0.18), but significantly decreased left atrial transport function.

Why the study?

Does limited left atrial surgical ablation compared to PVI alone maintain left atrial function in patients undergoing concomitant cardiac surgery?

Population

72 patients scheduled for valve surgery and/or coronary revascularization with atrial fibrillation…

Comparison

Limited left atrial surgical ablation… vs Epicardial pulmonary vein isolation only…

Design

Cohort

Follow-up

12 months

Authors

MCMarieke G. Compier LTL. F. Tops JBJerry Braun

Discussion

Member takes

Overview

May warrant caution with limited LA ablation in concomitant surgery; leaves open optimal strategies balancing rhythm and function.

Study Design

Type

Cohort (n=72)

Structured PICO

Does limited left atrial surgical ablation compared to PVI alone maintain left atrial function in patients undergoing concomitant cardiac surgery?

Population

72 patients with atrial fibrillation undergoing cardiac surgery, comparing limited left atrial surgical ablation to pulmonary vein isolation alone with 12-month follow-up.

Exposure

Limited left atrial surgical ablation (epicardial pulmonary vein isolation and additional endo-epicardial lines using bipolar radiofrequency) concomitant to cardiac surgery

Comparator

Epicardial pulmonary vein isolation (PVI) only concomitant to cardiac surgery

Outcome

Left atrial dimensions and function assessed on two-dimensional echocardiography at 3- and 12-month follow-upsurrogate

Main Result

Absolute Event Rate: 67% vs 81%

p-value: p=0.18

Limited left atrial surgical ablation during cardiac surgery decreases left atrial function and compliance compared to PVI alone, despite similar rates of sinus rhythm maintenance.

Cite This Study

synapsesocial.com/papers/6a21189b6bd086c0991e4a60 https://doi.org/10.1093/europace/euw106

Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

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