Key result
The trans-valvular impedance (TVI) inotropic index closely reproduced the sinus rate during beta-adrenergic stimulation, showing a linear correlation (r^2 > 0.7) in 25 of 28 patients.
Why the study?
Does a trans-valvular impedance (TVI) sensor accurately drive rate-responsive pacing following changes in inotropic regulation in patients undergoing pacemaker implantation?
Does a trans-valvular impedance (TVI) sensor accurately drive rate-responsive pacing following changes in inotropic regulation in patients undergoing pacemaker implantation?
Effect estimate: r^2 > 0.7
Trans-valvular impedance recording provides reliable hemodynamic information that can accurately regulate rate-responsive pacing during changes in inotropic state.
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TVI may support sensor-driven rate response in pacemaker patients; leaves open need for randomized trials before practice change.
GASPARINI et al. (2005) studied Patients requiring dual-chamber pacing (n=30). Trans-valvular impedance (TVI) detecting system vs. Intrinsic sinus rate was evaluated on Correlation between TVI inotropic index and sinus rate time-course (r^2 > 0.7). The trans-valvular impedance (TVI) inotropic index closely reproduced the sinus rate during beta-adrenergic stimulation, showing a linear correlation (r^2 > 0.7) in 25 of 28 patients.
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