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November 1, 1992Pacing and Clinical Electrophysiology

Intracardiac Impedance to Determine Sympathetic Activity in Rate Responsive Pacing

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Key result

ANS-controlled stimulation rate using intracardiac impedance demonstrated excellent agreement with spontaneous sinus rhythm during exercise in patients with AV block.

Why the study?

Does rate responsive pacing using intracardiac impedance to determine sympathetic activity provide physiological rate adaptation in patients with AV block?

Population

Patients with AV block

Comparison

Rate responsive pacing using intracardiac… vs Spontaneous sinus rhythm

Design

Cohort

Authors

MSM. SchaldachHelmholtz Centre for Environmental ResearchHHHelmut HuttenKlinikum Magdeburg

Discussion

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Implication

May support impedance-based rate response in AV block; hypothesis-generating and requires randomized outcome trials before practice change.

Structured PICO

Does rate responsive pacing using intracardiac impedance to determine sympathetic activity provide physiological rate adaptation in patients with AV block?

P
Population
Patients with AV block evaluated in a multicenter study using a standardized exercise protocol.
I
Intervention
Rate responsive pacing using intracardiac impedance to determine sympathetic activity (ANS-controlled stimulation rate)
C
Comparator
Spontaneous sinus rhythm
O
Outcome
Agreement between spontaneous sinus rhythm and ANS-controlled stimulation rate during different forms of exercisesurrogate

Rate responsive pacing using intracardiac impedance to measure sympathetic activity provides physiological rate adaptation during exercise in patients with AV block.

Cite This Study

Schaldach et al. (1992) studied AV block. ANS-controlled stimulation rate using intracardiac impedance vs. Spontaneous sinus rhythm was evaluated on Agreement between spontaneous sinus rhythm and ANS-controlled stimulation rate during exercise. ANS-controlled stimulation rate using intracardiac impedance demonstrated excellent agreement with spontaneous sinus rhythm during exercise in patients with AV block.

synapsesocial.com/papers/6a9e6ff4ea032eb126da2d19https://doi.org/10.1111/j.1540-8159.1992.tb02968.x
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Also Consider

Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Central Venous Oxygen Saturation for the Control of Automatic Rate‐Responsive Pacing*1982 · 89 citations
  2. 2A New Multisensor Pacing System Using Stroke Volume, Respiratory Rate, Mixed Venous Oxygen Saturation, And Temperature, Right Atrial Pressure, Right Ventricular Pressure, And dP/dt1988 · 39 citations
  3. 3Physiological Principles of a New Method for Rate Responsive Pacing Using the Pre‐ejection Interval1988 · 41 citations