Why the study?
Does dual chamber (DDDR) pacing improve objective exercise parameters compared to single chamber (VVIR) pacing in patients with chronotropic incompetence and left ventricular dysfunction?
Population
8 patients with DDDR pacemakers (implanted for chronotropic incompetence) and left ventricular dysfunction
Comparison
Dual chamber, rate responsive (DDDR) pacing mode vs Single chamber, ventricular rate responsive…
Design
RCT, randomized, blinded fashion
Follow-up
acute setting
Authors
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DDDR offers no exercise or hemodynamic advantage over VVIR; challenges routine dual-chamber preference in chronotropic incompetence with LV dysfunction.
Does dual chamber (DDDR) pacing improve objective exercise parameters compared to single chamber (VVIR) pacing in patients with chronotropic incompetence and left ventricular dysfunction?
In the acute setting, dual chamber rate responsive pacing does not provide objective improvements in exercise tolerance or hemodynamics compared to single chamber pacing in patients with chronotropic incompetence and left ventricular dysfunction.
Barrington et al. (1995) studied this question.
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