Key result
Dual chamber pacing with optimal AV delay improved quality of life and contractile parameters without affecting survival compared to medical therapy alone (26.3% vs 36.8% mortality at 6 months).
Why the study?
Does dual chamber pacing with optimal AV delay improve contractile parameters and quality of life in patients with congestive heart failure?
RCT (n=38)
randomized
Does dual chamber pacing with optimal AV delay improve contractile parameters and quality of life in patients with congestive heart failure?
Absolute Event Rate: 26.3% vs 36.8%
Dual chamber pacing with echo-optimized AV delay improves quality of life and specific echocardiographic parameters in patients with congestive heart failure, without significantly altering short-term survival.
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Supports AV-optimized dual-chamber pacing for QoL gains in HF; extends RCT evidence on contractile parameters without survival impact.
Alessandro Capucci (1999) conducted an RCT in congestive heart failure (n=38). Dual chamber pacemaker programmed to optimal AV delay vs. Optimal medical therapy was evaluated on Death. Dual chamber pacing with optimal AV delay improved quality of life and contractile parameters without affecting survival compared to medical therapy alone (26.3% vs 36.8% mortality at 6 months).
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