October 1, 1993Pacing and Clinical Electrophysiology
Improvement of Cardiac Function in Patients with Severe Congestive Heart Failure and Coronary Artery Disease by Dual Chamber Pacing with Shortened AV Delay
Key result
Dual chamber pacing with a short AV delay (100 msec) improved NYHA functional class from III-IV to II or II-III in 2 patients with severe heart failure refractory to medical therapy.
Why the study?
Does dual chamber pacing with shortened AV delay improve clinical status and NYHA class in patients with severe heart failure due to coronary artery disease?
Population
2 patients with severe heart failure due to coronary artery disease, refractory to medical therapy, baseline…
Design
Case_series
Follow-up
a few days
Authors
Discussion
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Member takes
Implication
May support short-AV dual-chamber pacing in refractory HF; hypothesis-generating and requires prospective RCTs before adoption.
Study Design
Type
Case Report (n=2)
Structured PICO
Does dual chamber pacing with shortened AV delay improve clinical status and NYHA class in patients with severe heart failure due to coronary artery disease?
P
Population
2 patients with severe heart failure due to coronary artery disease, refractory to medical therapy, baseline NYHA class III-IV with leg edema, ascites, dyspnea at rest, or orthopnea.
I
Intervention
Implantation of a physiological dual chamber pacemaker set with a short atrioventricular delay (100 msec).
O
Outcome
Improvement in clinical status and functional NYHA classpatient reported
Dual chamber pacing with a short AV delay may improve clinical symptoms and functional class in patients with severe, medically refractory heart failure.
Cite This Study
Auricchio et al. (1993) conducted a case report in Severe congestive heart failure and coronary artery disease (n=2). Dual chamber pacemaker with short atrioventricular delay was evaluated on Clinical status and functional NYHA class. Dual chamber pacing with a short AV delay (100 msec) improved NYHA functional class from III-IV to II or II-III in 2 patients with severe heart failure refractory to medical therapy.