Why the study?
Does DDDR pacing improve aerobic capacity compared to VVIR or DDD pacing in patients with chronotropic incompetence?
Population
16 patients with chronotropic incompetence and an implanted DDDR pacemaker. Subgroups included isolated…
Comparison
DDDR pacing mode during cardiopulmonary exercise… vs VVIR and DDD pacing modes, and sinus bradycardia…
Design
RCT, randomly studied by cardiopulmonary exercise testing
Authors
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Supports DDDR as preferred mode in chronotropic incompetence; confirms value of rate response plus AV synchrony in RCT.
Does DDDR pacing improve aerobic capacity compared to VVIR or DDD pacing in patients with chronotropic incompetence?
The conjunction of heart rate increase and preservation of AV synchrony (DDDR pacing) provides a significant improvement in aerobic capacity during exercise compared to VVIR or DDD modes in patients with chronotropic incompetence.
Lemke et al. (1992) studied this question.