Chronic fatigue syndrome is not a new medical condition. For centuries its confusing array of features has been attributed to numerous environmental, metabolic, infectious, immunologic, and psychiatric disturbances. This is a review and critique of many of these alternative diagnoses, sufficient to provide a historical background for current thinking about the disorder.
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Stephen E. Straus (1991) studied this question.
Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context: