Key result
Postprocedural TIMI flow independently predicted in-hospital mortality in patients with acute left main coronary total occlusion undergoing emergency PCI (OR 0.23; 95% CI 0.1-0.36; p<0.001).
Why the study?
Acute total occlusion of the left main coronary artery usually leads to a catastrophic presentation, but limited and inconsistent data have been reported.
Population
46 patients with myocardial infarction due to confirmed ATOLMA undergoing emergency PCI
Design
Multicenter retrospective cohort study
Follow-up
One-year
Authors
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May support targeting optimal TIMI flow in emergency left main PCI; leaves open confirmation in prospective studies.
Cohort (n=46)
Yes
Odds Ratio: 0.23 (95% CI 0.1–0.36)
p-value: p=<0.001
In patients with acute total occlusion of the left main coronary artery, presentation is catastrophic with high mortality, but primary angioplasty is feasible and postprocedural TIMI flow strongly predicts in-hospital survival.
Gutiérrez et al. (2020) conducted a cohort in Acute total occlusion of the left main coronary artery (ATOLMA) (n=46). Postprocedural TIMI flow was evaluated on In-hospital mortality (OR 0.23, 95% CI 0.1-0.36, p=<0.001). Postprocedural TIMI flow independently predicted in-hospital mortality in patients with acute left main coronary total occlusion undergoing emergency PCI (OR 0.23; 95% CI 0.1-0.36; p<0.001).
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