Key result
The minimalistic and precise approach for TAVI significantly reduced the need for permanent pacemaker implantation to 9.0% compared to 25.5% with the standard approach.
Why the study?
Increasing TAVI frequency and clinical experience have created a need for procedural improvement and standardization, including simplification toward a PCI-like procedure.
Does a minimalistic and precise approach improve safety and efficiency compared to a standard approach in patients undergoing TAVI?
Cohort (n=208)
No
Does a minimalistic and precise approach improve safety and efficiency compared to a standard approach in patients undergoing TAVI?
A minimalistic and precise approach to TAVI using awake sedation and fully percutaneous access is safe and significantly reduces ICU stay, hospital stay, and the need for permanent pacemaker implantation.
May support minimalistic TAVI in select patients; leaves open randomized confirmation before practice change.
Since the first procedure in humans in 2002, transcatheter aortic valve implantation (TAVI) has evolved from innovative procedure of the future to treatment of choice in high-risk patients with potential to become a routine procedure in the near future. Thanks to the excellent safety profile, the emerging evidence from clinical trials, TAVI has raised its class of recommendation in the guidelines. The constantly upraising frequency of TAVI and the experience gained have led to the need of procedure improvement and standardization. Between 2013 and 2021 208 patients underwent TAVI in our cardiovascular center. The standard approach was used for 141 of them and the minimalistic and precise approach for the rest 67 patients. The main focus of this manuscript is improvement of the procedure results, quality of life and comfort of the patients, while providing a better pharmacoeconomic profile.The minimalistic and precise protocol of implantation and the vascular device closure are thoroughly described. The safety and the efficiency of the minimalistic and precise approach compared to the standard one, which is considered the ”gold standard” are proven. At the same time the minimalistic approach is described as superior to the standard one in using the radial artery as second vascular approach to reduce vascular complications and bleeding. Other advantage of the minimalistic approach is the implantation of the transcatheter aortic valve in position 0/1 while using rapid pacing, to reduce the frequency of pacemaker implantation, reduction of paravalvular leak and reduction of hospital stay. TAVI has proved to be an alternative to surgical aortic valve replacement in high risk patients and in the past years also in intermediate and low risk patients. In order TAVI to become a PCI-like procedure it must be simplified. That is exactly why the minimalistic and precise approach for TAVI is needed and it is the future of the procedure.
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Petrov et al. (2022) conducted a cohort in Aortic stenosis (n=208). Minimalistic and precise approach for TAVI (conscious sedation, fully percutaneous access, rapid pacing) vs. Standard approach for TAVI (general anesthesia, surgical or percutaneous access, no rapid pacing) was evaluated on Permanent pacemaker implantation (p=0.005). The minimalistic and precise approach for TAVI significantly reduced the need for permanent pacemaker implantation to 9.0% compared to 25.5% with the standard approach.
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