Online mindfulness training in percutaneous coronary intervention: a randomized clinical trial

Background: Mindfulness training exhibits favorable effects on both psychological and physiological outcomes. We aimed at assessing its effects on post-percutaneous coronary intervention (PCI) patients. Methods: We recruited 357 patients arranged with PCI and randomized them in a ratio of 1:1 (n = 178 versus n = 179) into a 3-month mindfulness training class in addition to usual care. The primary outcomes were the physiological and health-related quality of life outcomes of patients post-PCI. The secondary outcomes were the psychological outcomes of the patients. Results: Compared to the control group, the 3-month mindfulness training improved the physiological outcomes including systolic blood pressure, body mass index, total cholesterol level, low-density lipoprotein-cholesterol, and triglyceride levels of patients post-PCI. The psychological outcomes including depression, anxiety, self-efficacy, and stress of these patients were also improved statistically. Conclusion: Mindfulness training exhibited benefits on both physiological and psychological outcomes of patients post-PCI.