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January 1, 2018Canadian Respiratory JournalOpen Access

The Effects of Continuous Positive Airway Pressure on Premature Ventricular Contractions and Ventricular Wall Stress in Patients with Heart Failure and Sleep Apnea

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Why the study?

Does CPAP treatment reduce premature ventricular contractions, electrocardiographic arrhythmia indices, and NT-pro-BNP levels in patients with heart failure, an ICD, and newly diagnosed OSAS?

Population

Patients with heart failure, an implantable cardioverter defibrillator, and newly diagnosed obstructive…

Comparison

Continuous positive airway pressure treatment vs Control group without CPAP treatment

Design

Cohort

Follow-up

6 months

Authors

SSSabri SeyisDoğuş UniversityAUAdnan Kazım UsalanTarsus UniversityİRİbrahim RencüzoğullarıInterventional Cardiology

Discussion

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Implication

CPAP associated with lower PVCs and NT-proBNP in HF-OSAS; leaves open need for RCTs before practice change.

Structured PICO

Does CPAP treatment reduce premature ventricular contractions, electrocardiographic arrhythmia indices, and NT-pro-BNP levels in patients with heart failure, an ICD, and newly diagnosed OSAS?

P
Population
Patients with heart failure, an implantable cardioverter defibrillator (ICD), and newly diagnosed obstructive sleep apnea syndrome (OSAS)
I
Intervention
Continuous positive airway pressure (CPAP) treatment
C
Comparator
Control group without CPAP treatment
O
Outcome
Premature ventricular contraction load, electrocardiographic arrhythmia indices (T-peak to T-end, corrected QT, corrected QT dispersion, T-peak to T-end/corrected QT ratio), ICD shocks, and NT-pro-BNP levels at 6 monthssurrogate

CPAP treatment in patients with heart failure and obstructive sleep apnea may reduce ventricular arrhythmia burden and ventricular wall stress as measured by NT-pro-BNP.

Limitations

  • Results need to be clarified with further studies

Cite This Study

Seyis et al. (2018) studied this question.

synapsesocial.com/papers/6a212bd6570f73dd9ac3c834https://doi.org/10.1155/2018/2027061

Topics

Cardiac device therapyHFrEF treatmentHeart failure
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