Why the study?
Does speckle-tracking based strain analysis detect early-stage cardiac deformation in a Type I diabetic Akita mouse model?
Population
Male Akita (Ins2WT/C96Y) mice
Comparison
Speckle-tracking based strain analyses vs Conventional echocardiographic analysis
Design
Preclinical
Follow-up
various ages (starting at 12 weeks)
Authors
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Strain analysis may flag early diabetic cardiomyopathy in models; leaves open human validation before clinical adoption.
Does speckle-tracking based strain analysis detect early-stage cardiac deformation in a Type I diabetic Akita mouse model?
Speckle-tracking echocardiography can detect early-stage cardiac deformation in diabetic cardiomyopathy before conventional echocardiography.
Zhou et al. (2018) studied this question.
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