Why the study?
Do cardiac hormones decrease the number and proliferation of human small-cell lung cancer cells in culture?
Population
Human small-cell lung cancer cells in culture
Design
Preclinical
Follow-up
96 hours
Authors
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Should not yet change lung cancer management; leaves open whether natriuretic peptides merit in vivo testing.
Do cardiac hormones decrease the number and proliferation of human small-cell lung cancer cells in culture?
Five cardiac natriuretic peptide hormones significantly decrease the number and proliferation of human small-cell lung cancer cells in vitro, mediated partly by cyclic GMP.
Vesely et al. (2005) studied this question.
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