Why the study?
Does systematic rotation through five classes of antihypertensive drugs improve blood pressure control and identify optimal individual therapy in young hypertensives?
Does systematic rotation through five classes of antihypertensive drugs improve blood pressure control and identify optimal individual therapy in young hypertensives?
Systematic rotation through different antihypertensive classes demonstrates reproducible individual variation in response, supporting an AB/CD scheme for choosing initial therapy.
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Supports rotation to optimize monotherapy in young hypertensives; extends evidence for individualized AB/CD selection.
Deary et al. (2002) studied this question.
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