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January 1, 2025Skin CancerOpen Access

A case of primary subcutaneous myxoid liposarcoma in the right thigh

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Key result

Surgical excision with a 2.5 cm margin resects primary subcutaneous myxoid liposarcoma of the thigh.

Why the study?

Primary subcutaneous occurrence of liposarcoma is considered rare.

Population

One 55-year-old male with primary subcutaneous myxoid liposarcoma of the right thigh

Design

Case report

Authors

NKNaoya KUROGIUniversity of MiyazakiKMKosuke MOCHIDAUniversity of MiyazakiKMKazuya MaekawaUniversity of Miyazaki

Discussion

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Implication

May prompt inclusion of myxoid liposarcoma in differentials for subcutaneous thigh masses; leaves open optimal margins and surveillance in larger cohorts.

Structured PICO

P
Population
55-year-old male with a mass in the right thigh, subsequently diagnosed as primary subcutaneous myxoid liposarcoma
I
Intervention
Surgical excision with a 2.5 cm margin including part of the vastus lateralis muscle
O
Outcome
Histopathological and immunohistochemical diagnosis

This report documents a rare case of primary subcutaneous myxoid liposarcoma, which infrequently occurs in the dermis and subcutaneous tissue.

Cite This Study

KUROGI et al. (2025) studied this question. Primary subcutaneous myxoid liposarcoma of the right thigh was diagnosed via immunohistochemistry and excised with a 2.5 cm margin in a 55-year-old man.

synapsesocial.com/papers/6a214077e06b4fc4c1ab87bchttps://doi.org/10.5227/skincancer.40.36
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Liposarcoma A study of 55 cases with a reassessment of its classification1979 · 557 citations
  2. 2Myxoid/Round Cell Liposarcoma of the Extremities1996 · 178 citations
  3. 3The clinicopathologic spectrum of myxoid and round cell liposarcoma: A study of 95 cases1996 · 276 citations
  4. 4Primary subcutaneous myxoid liposarcoma: a clinicopathologic review of three cases with molecular confirmation and discussion of the differential diagnosis2014 · 24 citations
  5. 5Unplanned Excision in Soft Tissue Sarcoma: Current Knowledge and Remaining Gaps2025 · 8 citations