Why the study?
Does hypercapnia-induced shear stress mediate dilation of the internal carotid artery in humans?
Population
18 human subjects
Comparison
Hypercapnia (6% carbon dioxide) vs Rest (baseline)
Design
Other
Authors
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Should not yet change clinical cerebrovascular assessment; supports shear mediation but remains hypothesis-generating pending prospective trials.
Does hypercapnia-induced shear stress mediate dilation of the internal carotid artery in humans?
This study provides the first evidence in humans that shear stress is an important stimulus for hypercapnic vasodilation of the internal carotid artery.
Carter et al. (2016) studied this question.
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