Key result
Initial shockable rhythm linked to ~9.3-fold higher 30-day survival after out-of-hospital cardiac arrest.
Why the study?
Despite advances in treating heart diseases, outcomes for patients with sudden cardiac arrest remain poor, prompting evaluation of prehospital predictors of survival in OHCA.
Do prehospital variables such as shockable initial rhythm and bystander CPR improve survival outcomes in out-of-hospital cardiac arrest victims?
Cohort (n=381)
No
Do prehospital variables such as shockable initial rhythm and bystander CPR improve survival outcomes in out-of-hospital cardiac arrest victims?
A shockable initial rhythm, younger age, and bystander CPR are vital factors for improving survival and neurological outcomes after out-of-hospital cardiac arrest.
Background and Objectives: Despite advances in the treatment of heart diseases, the outcome of patients experiencing sudden cardiac arrest remains poor. The aim of our study was to determine the prehospital variables as predictors of survival outcomes in out-of-hospital cardiac arrest (OHCA) victims. Materials and Methods: This was a retrospective observational cohort study of OHCA cases. EMS protocols created in accordance with the Utstein style reporting for OHCA, first responder intervention reports, medical dispatch center dispatch protocols and hospital medical reports were all reviewed. Multivariate logistic regression was performed with the following variables: age, gender, witnessed status, location, bystander CPR, first rhythm, and etiology. Results: A total of 381 interventions with resuscitation attempts were analyzed. In more than half (55%) of them, bystander CPR was performed. Thirty percent of all patients achieved return of spontaneous circulation (ROSC), 22% of those achieved 30-day survival (7% of all OHCA victims), and 73% of those survived with Cerebral Performance Score 1 or 2. The logistic regression model of adjustment confirms that shockable initial rhythm was a predictor of ROSC [OR: 4.5 (95% CI: 2.5–8.1)] and 30-day survival [OR: 9.3 (95% CI: 2.9–29.2)]. Age was also associated (≤67 years) [OR: 3.9 (95% CI: 1.3–11.9)] with better survival. Conclusions: Elderly patients have a lower survival rate. The occurrence of bystander CPR in cardiac arrest remains alarmingly low. Shockable initial rhythm is associated with a better survival rate and neurological outcome compared with non-shockable rhythm.
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Strnad et al. (2023) conducted a cohort in Out-of-hospital cardiac arrest (OHCA) (n=381). Shockable initial rhythm vs. Non-shockable initial rhythm was evaluated on 30-day survival (OR 9.3, 95% CI 2.9-29.2). A shockable initial rhythm was a strong independent predictor of 30-day survival (OR 9.3) in victims of out-of-hospital cardiac arrest.
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