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December 11, 2025CureusOpen Access

Obesity and prolonged hospital stay linked to higher surgical site infections after CABG.

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Why the study?

Surgical site infections remain a serious complication after CABG, and the study aimed to determine their incidence and identify associated factors in patients at intermediate to high risk.

Are obesity and prolonged hospital stay associated with surgical site infections in intermediate- to high-risk patients undergoing CABG?

Population

51 intermediate- to high-risk patients undergoing CABG via median sternotomy

Comparison

Patients developing surgical site infections vs those who did not

Design

Single-center observational study

Key result

Obesity and prolonged hospital stay were significantly associated with a higher incidence of surgical site infections (33.3% overall rate) in intermediate- to high-risk patients after CABG.

Authors

PKParaskevi KyriaziMediterranean UniversityAPAthina PatelarouMediterranean UniversityΘΚΘεόδωρος ΚατσούλαςNational and Kapodistrian University of Athens

Discussion

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Member takes

Overview

Supports heightened SSI vigilance in obese CABG patients with extended stays; hypothesis-generating and should not yet change practice.

Study Design

Type

Observational (n=51)

Multicenter

No

Structured PICO

Are obesity and prolonged hospital stay associated with surgical site infections in intermediate- to high-risk patients undergoing CABG?

P
Population
51 intermediate- to high-risk adult patients undergoing isolated CABG via median sternotomy at a single center in Greece, followed for 6 months to assess surgical site infections.
O
Outcome
Incidence of surgical site infections (SSIs) evaluated postoperatively using the ASEPSIS scoring system over 6 months follow-upsafety

Main Result

Effect estimate: ρ = 0.512 for hospital stay; f = 0.348 for obesity

p-value: p=<0.001 for hospital stay; 0.013 for obesity

In intermediate- to high-risk patients undergoing CABG, obesity and prolonged hospital stay are significantly associated with a higher incidence of surgical site infections.

Limitations

  • Small sample size
  • Single-center design
  • Limited number of examined variables
  • Lack of multivariate analysis
  • Assessors were aware of patient characteristics (unblinded assessment)
  • Lack of blinded assessment for SSI
  • Lack of multivariate analysis to adjust for confounders

Cite This Study

Kyriazi et al. (2025) conducted an observational in Coronary artery disease undergoing CABG (n=51). Obesity and prolonged hospital stay vs. Non-obese and shorter hospital stay was evaluated on Incidence of surgical site infections (SSIs) (ρ = 0.512 for hospital stay; f = 0.348 for obesity, p=<0.001 for hospital stay; 0.013 for obesity). Obesity and prolonged hospital stay were significantly associated with a higher incidence of surgical site infections (33.3% overall rate) in intermediate- to high-risk patients after CABG.

synapsesocial.com/papers/6a2148c2e06b4fc4c1ab8de6https://doi.org/10.7759/cureus.99013
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Analysis of Characteristics and Risk Factors of Surgical Site Infection after Coronary Artery Bypass Graft2016 · 1 citations
  2. 2Does the anthropometric profile influence infection morbidity after coronary artery bypass grafting?2021 · 2 citations
  3. 3Risk Features for Surgical-Site Infections in Coronary Artery Bypass Surgery1998 · 33 citations
  4. 4Risk Features for Surgical-Site Infections in Coronary Artery Bypass Surgery1998 · 29 citations
  5. 5Incidence and factors associated with surgical site infection following coronary artery bypass grafting in Nepal: a prospective single-center study2026