Key result
Heavy lifetime cannabis use was associated with higher arterial stiffness index levels in middle-aged men (b = 0.19; 95% CI 0.02-0.35), but not in women.
Why the study?
No studies had investigated the association between arterial stiffness index and cannabis use in a middle-aged general population.
Does cannabis use increase arterial stiffness index in a middle-aged general population?
Population
46 219 volunteers of the middle-aged UK Biobank population
Comparison
Cannabis use aspects (lifetime, frequency, and current status)
Design
Cross-sectional analysis
Authors
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Should not yet change clinical advice on cannabis; leaves open causal inference for sex-specific arterial stiffness associations.
Cross-Sectional (n=46,219)
Does cannabis use increase arterial stiffness index in a middle-aged general population?
Mean Difference: 0.19 (95% CI 0.02–0.35)
Heavy lifetime and current cannabis use is associated with increased arterial stiffness in middle-aged men, but not women.
Alexandre Vallée (2023) conducted a cross-sectional in General population (n=46,219). Cannabis use vs. Non-users was evaluated on Arterial stiffness index (ASI) (b = 0.19, 95% CI 0.02-0.35). Heavy lifetime cannabis use was associated with higher arterial stiffness index levels in middle-aged men (b = 0.19; 95% CI 0.02-0.35), but not in women.
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