Key result
Sympathetic baroreflex gain links to resting BP in males but not females.
Cross-Sectional (n=191)
This study highlights sex differences in the neural regulation of blood pressure, demonstrating that sympathetic baroreflex gain is associated with resting blood pressure in males but not females.
Does not support clinical use of sympathetic measures for BP assessment; hypothesis-generating for sex differences in autonomic regulation.
In a sample of 191 normotensive young adults, we confirm that resting muscle sympathetic nerve activity is a poor predictor of resting blood pressure and now demonstrate that sympathetic baroreflex gain is associated with resting blood pressure in males but not females. In contrast, signal-averaged measures of sympathetic-blood pressure transduction are unrelated to resting blood pressure. These findings highlight sex differences in the neural regulation of blood pressure.
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Nardone et al. (2024) conducted a cross-sectional in Normotension (n=191). Sympathetic baroreflex gain and resting muscle sympathetic nerve activity was evaluated on Resting blood pressure. Sympathetic baroreflex gain is associated with resting blood pressure in males but not females, whereas resting muscle sympathetic nerve activity is a poor predictor overall.
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