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May 26, 2009HypertensionOpen Access

Age-Related Differences in the Sympathetic-Hemodynamic Balance in Men

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Why the study?

Do older normotensive men exhibit a different sympathetic-hemodynamic balance compared to younger men?

Population

31 normotensive men (17 older men and 14 younger men)

Design

Cross-sectional

Key result

Older age in normotensive men was associated with a positive relationship between muscle sympathetic nerve activity and diastolic blood pressure (r=0.49; P=0.05), which was absent in younger men.

Authors

EHEmma C. HartMJMichael J. JoynerBWB. Gunnar Wallin

Discussion

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Overview

Does not inform hypertension management; leaves open whether compensatory balance fails with aging.

Study Design

Type

Cross-Sectional (n=31)

Structured PICO

Do older normotensive men exhibit a different sympathetic-hemodynamic balance compared to younger men?

P
Population
31 normotensive men (17 older, 14 younger) evaluated for age-related differences in sympathetic-hemodynamic balance.
C
Comparator
Younger normotensive men
O
Outcome
Relationship between muscle sympathetic nerve activity and diastolic blood pressure, cardiac output, and alpha-adrenergic responsivenesssurrogate

Main Result

Effect estimate: r=0.49

p-value: p=0.05

Cite This Study

Hart et al. (2009) conducted a cross-sectional in Normotension (n=31). Older age vs. Younger men was evaluated on Relationship between muscle sympathetic nerve activity and diastolic blood pressure (r=0.49, p=0.05). Older age in normotensive men was associated with a positive relationship between muscle sympathetic nerve activity and diastolic blood pressure (r=0.49; P=0.05), which was absent in younger men.

synapsesocial.com/papers/6a62f031cd7899abd6b6ddc2https://doi.org/10.1161/hypertensionaha.109.131417
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