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September 1, 1976Neurology

Incidence of Z band streaming and myofibrillar disruptions in skeletal muscle from healthy young people

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Population

34 healthy young volunteers providing skeletal muscle tissue from the vastus lateralis or peroneus brevis…

Design

Cross-sectional

Authors

HMH.Y. MeltzerNorthwestern UniversityRKRalph W. KunclBryn Mawr CollegeJCJames ClickColorado Permanente Medical Group

Discussion

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Overview

Establishes normative thresholds for Z band streaming in healthy muscle; leaves open diagnostic cutoffs pending disease-cohort validation.

Structured PICO

P
Population
34 healthy young volunteers providing skeletal muscle tissue from the vastus lateralis or peroneus brevis muscles
O
Outcome
Incidence and quantification of focal and extensive areas of Z band streaming and disruption of myofibrillar architecturesurrogate

This study establishes baseline quantitative data for Z band streaming and myofibrillar disruptions in healthy skeletal muscle, aiding in the identification of pathologic lesions.

Cite This Study

Meltzer et al. (1976) studied this question.

synapsesocial.com/papers/6a2152e4e06b4fc4c1ab93d9https://doi.org/10.1212/wnl.26.9.853
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Also Consider

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  1. 1Comparison of skeletal muscle ultrastructural changes between normal and blood flow‐restricted resistance exercise: A case report2021 · 12 citations
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  4. 4Atomic Force Microscopic Evidence for Z-band as a Rigid Disc Fixing the Sarcomere Structure of Skeletal Muscle.2000 · 9 citations
  5. 5Structural states in the Z band of skeletal muscle correlate with states of active and passive tension.1988 · 40 citations