Adams-Stokes Syndrome Associated With Chronic Heart Block

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Why the study?

Does prednisone therapy improve heart block and prevent syncope in patients with Adams-Stokes syndrome?

Population

6 patients with Adams-Stokes syndrome associated with chronic heart block

Design

Case_series

Authors

Discussion

May support steroid use in Adams-Stokes syndrome; hypothesis-generating and should not yet change practice.

Does prednisone therapy improve heart block and prevent syncope in patients with Adams-Stokes syndrome?

Population

6 patients with Adams-Stokes syndrome associated with chronic heart block

Intervention

Prednisone therapy (initially 60 mg per day, sometimes reduced to 30 mg per day)

Outcome

Diminution or elimination of heart block and abolition of associated attacks of syncope

Prednisone therapy may be effective in temporarily or permanently eliminating syncope attacks and heart block in patients with Adams-Stokes syndrome.

Charles K. Friedberg (1960) studied this question.

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