Population
1396 backcross mice (SJL/J x BALB/cJ) and 271 backcross mice (129S6/SvEvTac x BALB/cJ)F(1) x BALB/cJ
Design
Preclinical
Authors
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Localizes MAV-1 susceptibility to Ly6 cluster in mice; leaves open functional validation and human translation.
The major host factor for mouse adenovirus type 1 susceptibility maps to the Ly6 gene family on chromosome 15.
Spindler et al. (2010) studied this question.
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