What question did this study set out to answer?

The research aims to analyze how striated muscle fibers respond to quick changes in load.

June 1, 1966The Journal of PhysiologyOpen Access

Contraction kinetics of striated muscle fibres following quick changes in load

View Full Paper

Ask AI

Bookmark

Population

Single striated muscle fibres and small fibre bundles from the frog and the toad

Design

Preclinical

Authors

MCM. M. CivanErciyes University RPRichard J. PodolskyNational Institutes of Health

Discussion

Member takes

Implication

Warrants caution before clinical translation; extends Huxley's model of contractile mechanisms in animal preparations.

Key Points

The research aims to analyze how striated muscle fibers respond to quick changes in load.
Measured contraction kinetics of single striated muscle fibers and bundles from frog and toad.
Simultaneous recordings of displacement and force during load changes.
Characterized transient dynamics using displacement deviation and null times.
Contractile force reached a steady value before contraction velocity stabilized.
Transient velocity averaged to be equal to the final steady velocity.
Null time and steady velocity (V(max)) independence from temperature indicates origin in the contractile mechanism.

Structured PICO

Population

Single striated muscle fibres and small fibre bundles from the frog and the toad

Intervention

Quick changes in load from P(0) to L < P(0)

Outcome

Contraction kinetics (displacement and force, time required for isotonic contraction to become steady)surrogate

Isotonic velocity transients following step changes in load originate in the contractile mechanism, with characteristic dimensions comparable to Huxley's 1957 model.

Cite This Study

Civan et al. (1966) studied this question.

synapsesocial.com/papers/6a215c736edeeecbd303001f https://doi.org/10.1113/jphysiol.1966.sp007929

View Full Paper

Ask AI

Bookmark

Contraction kinetics of striated muscle fibres following quick changes in load

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Contraction kinetics of striated muscle fibres following quick changes in load

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Also Consider

Also Consider