Key result
Elevated plasma free fatty acid levels were identified as an independent risk factor and a sensitive and specific diagnostic marker for acute myocardial infarction.
Why the study?
The study was conducted to clarify the diagnostic value of the circulating free fatty acid level for acute myocardial infarction in patients with coronary heart disease.
Does the circulating plasma free fatty acid level serve as a diagnostic marker for acute myocardial infarction in patients undergoing coronary angiography?
Observational (n=1,776)
Does the circulating plasma free fatty acid level serve as a diagnostic marker for acute myocardial infarction in patients undergoing coronary angiography?
Answers are grounded in this paper and cite their sources.
Elevated plasma free fatty acid levels may serve as an independent diagnostic marker and risk factor for acute myocardial infarction in patients with coronary heart disease.
Aim: To clarify the diagnostic value of the circulating free fatty acid (FFA) level for acute myocardial infarction (AMI) in coronary heart disease patients. Methods & results: A total of 1776 patients were screened by coronary angiography from October 2014 to February 2016. The plasma FFA level was significantly higher in coronary heart disease patients with lesions in three or more vessels than those with lesions in one or two vessels. Moreover, an elevated FFA level was identified as an independent risk factor for AMI on multivariate regression analysis and shown to be a sensitive and specific indicator for AMI diagnosis by receiver operating characteristic curve analysis. Conclusion: An elevated FFA level is an independent risk factor and independent diagnostic marker for AMI.
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Kan et al. (2020) conducted an observational in Acute myocardial infarction (n=1,776). Elevated plasma free fatty acid level vs. Lower plasma free fatty acid level was evaluated on Acute myocardial infarction diagnosis. Elevated plasma free fatty acid levels were identified as an independent risk factor and a sensitive and specific diagnostic marker for acute myocardial infarction.
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