Key result
This review summarizes available evidence on the clinical performance of direct oral anticoagulants in atrial fibrillation patients undergoing various cardiac interventional procedures.
Why the study?
The role of direct oral anticoagulants in cardiac interventional procedures is a pressing clinical question given increasing procedures and patients receiving DOAC therapy.
What is the clinical performance of DOACs in patients undergoing cardiac interventional procedures?
What is the clinical performance of DOACs in patients undergoing cardiac interventional procedures?
This review provides an update on the clinical performance of DOACs in patients with and without atrial fibrillation undergoing cardiac interventional procedures.
May inform periprocedural DOAC strategies in AF; leaves open need for procedure-specific RCTs.
Direct oral anticoagulants (DOACs) are considered a first-line therapy for long-term stroke prevention in patients with nonvalvular atrial fibrillation (AF) and high thromboembolic risk. The potential role of DOACs in cardiac interventional procedures is a pressing clinical question, considering the increasing number of procedures and the growing prevalence of patients in DOAC therapy. The aim of this review is to provide an update on available evidence about the clinical performance of DOACs in AF patients undergoing different interventional procedures (AF cardioversion and ablation, and percutaneous coronary and structural heart disease interventions) and to explore the possible role of DOACs as an alternative therapeutic strategy in cardiac interventional procedures among non-AF patients.
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Melillo et al. (2019) conducted a review in Atrial fibrillation. Direct oral anticoagulants (DOACs) was evaluated. This review summarizes available evidence on the clinical performance of direct oral anticoagulants in atrial fibrillation patients undergoing various cardiac interventional procedures.
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