Key result
Transthoracic ventricular defibrillation with 40-, 80-, and 100-amp shocks induced a much larger incidence of arrhythmias compared to 10- and 20-amp shocks at any given energy level in dogs.
Why the study?
Does the current strength and duration of unidirectional rectangular pulse defibrillation affect the incidence of induced arrhythmias in dogs with ventricular fibrillation?
Does the current strength and duration of unidirectional rectangular pulse defibrillation affect the incidence of induced arrhythmias in dogs with ventricular fibrillation?
In a canine model of ventricular fibrillation, higher current amplitude and energy content during defibrillation with unidirectional rectangular stimuli are associated with a greater incidence of induced arrhythmias.
Answers are grounded in this paper and cite their sources.
Higher-current defibrillation may increase post-shock arrhythmias; leaves open optimal parameters for clinical translation.
The incidence of the various types of arrhythmia induced by defibrillation in anesthetized dogs that had had continous ventricular fibrillation for 30 seconds was studied as a function of the current strengh and the duration of the unidirectional rectangular pulse used to terminate the fibrillation. Shocks at 10, 20, 40, 80, and 100 amp with durations in the range of 80 µsec through 64 msec were used. At any given energy level the incidence of induced arrhythmias was much larger for the 40-, 80-, and 100-amp shocks than for the 10- and 20-amp shocks. At 10 and 20 amp, the incidence of induced arrhythmias increased with increasing energy content. Premature ventricular contractions were observed at nearly all levels of energy and current, in contrast to other types of arrhythmias that appear to be strongly related to energy content or current amplitude or both.
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Stoeckle et al. (1968) studied Ventricular fibrillation. Transthoracic ventricular defibrillation with unidirectional rectangular stimuli vs. Different current strengths and energy levels was evaluated on Incidence of various types of arrhythmia induced by defibrillation. Transthoracic ventricular defibrillation with 40-, 80-, and 100-amp shocks induced a much larger incidence of arrhythmias compared to 10- and 20-amp shocks at any given energy level in dogs.
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